Burette
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Molecular workspace for Mac

Press Space.
See the molecule.

Preview molecular files in Finder. Open Burette to compare, edit, and export.

Download for macOSTry in your browser

Free and open source.

A musical demonstration with no speech. Pressing Space in Finder opens a molecular structure in Quick Look. Burette previews proteins, molecules, trajectories, spectra and collections, with Finder thumbnails and over 100 file types. The workspace compares structures side by side, browses compound collections, maps chemical space, exports figures, and shows docking poses and ligand pockets. An agent opens 1HTB and focuses on NAD. The film ends: Burette. Press Space. See the molecule. Free and open source.

Open workspace

See Burette in action.

All features ↗

Inspect a binding pocket.

Compare molecular poses.

Explore Chemical Space.

Create molecular illustrations.

Start in Finder

Preview a structure.
Right in Finder.

Select a molecular file and press Space. Rotate it, zoom in, and see what is inside before opening the workspace.

Explore Quick Look ↗

Inspect the structure

The whole protein.
The detail you need.

Find chains and ligands in the scene tree. Hide what gets in the way, select a component, and bring it into view.

Explore selection and analysis ↗

Work with a collection

Find the compounds
you want to work with.

Browse molecular structures, compare their properties, and narrow your selection. Export the compounds you want to work with.

Explore collections ↗

Fits your workflow

The files you
already work with.

View all supported formats
Structures & trajectories

PDB, CIF, mmCIF, SDF, MOL, MOL2, XYZ, GRO, MAE

Interactive molecular views with Mol*.

Collections & reactions

SMILES, CSV, TSV, SD, DWAR, RXN, RDF

Structures and properties, ready to search and compare.

Quantum chemistry

CUBE, LOG, OUT, PSI4, VASP

Vector artwork with the optional xyzrender engine.

Burette for agents

Your agent can
work here too.

Ask Codex to open a structure or focus on a ligand with the Burette plugin. Inspect the result in the molecular workspace and continue working with the mouse or your next prompt.

Set up the plugin

Installation

Install Burette.
Start in Finder.

macOS 12+ · Apple Silicon and Intel

Installation guide

Download Burette, move it to Applications, and open it once to register Finder previews. Or install with Homebrew:

  1. $ brew tap SergeiNikolenko/burette
  2. $ brew install --cask burette

Public downloads are ad-hoc signed. macOS may require first-launch approval in System Settings → Privacy & Security.

A few practical details

Good to know.

Take a closer look.

Burette is free and open source. Made for your Mac.

Download for macOS